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Oxandrolone Troches

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Oxandrolone is a synthetic testosterone derivative administered orally. Due to the removal of the methyl group from the C-19 position, it has anabolic effects that are stronger than androgenic effects. Oxandrolone has anabolic potential that is between three and thirteen times more than that of testosterone and methyltestosterone. Oxandrolone is helpful for increasing weight gain after burns or trauma as well as in some disease states including COPD and AIDS when combined with enough calories. The increase in weight is mostly the result of elevated lean body mass as opposed to increased body fat, which is frequently seen with nutritional supplements. When a medicine is stopped, the positive effects on lean body mass are lost. In order to counteract the protein catabolism brought on by extended corticosteroid treatment, oxandrolone is employed. Supportive data also exist for the treatment of patients with Duchenne’s muscular dystrophy, constitutional delay of growth and puberty, HIV wasting syndrome and associated muscle weakness, and short stature associated with Turner’s syndrome. Conflicting evidence exists as to whether or not anabolic steroids significantly increase athletic performance by increasing muscle strength, but the NCAA and IOC currently prohibit their use by athletes. Oxandrolone is not ergogenic at labeled doses but athletes often use higher doses; athletic use should be discouraged due to the risk for dyslipidemia, potential hepatotoxicity, and other serious side effects. Oxandrolone was approved by the FDA in July 1964 and became a controlled substance in 1991.

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503A vs 503B

  • 503A pharmacies compound products for specific patients whose prescriptions are sent by their healthcare provider.
  • 503B outsourcing facilities compound products on a larger scale (bulk amounts) for healthcare providers to have on hand and administer to patients in their offices.

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